Dolobasan
Brand names,
Dolobasan
Analogs
Dolobasan
Brand Names Mixture
Dolobasan
Chemical_Formula
C14H11Cl2NO2
Dolobasan
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Dolobasan
fda sheet
Dolobasan
msds (material safety sheet)
Dolobasan
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Dolobasan
Molecular Weight
296.148 g/mol
Dolobasan
Melting Point
283-285oC
Dolobasan
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Dolobasan
State
solid
Dolobasan
LogP
4.218
Dolobasan
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Dolobasan
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Dolobasan
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Dolobasan
Absorption
Completely absorbed from the gastrointestinal tract.
Dolobasan
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Dolobasan
Patient Information
Dolobasan
Organisms Affected
Humans and other mammals