Cataflam
Brand names,
Cataflam
Analogs
Cataflam
Brand Names Mixture
Cataflam
Chemical_Formula
C14H11Cl2NO2
Cataflam
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Cataflam
fda sheet
Cataflam
msds (material safety sheet)
Cataflam
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Cataflam
Molecular Weight
296.148 g/mol
Cataflam
Melting Point
283-285oC
Cataflam
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Cataflam
State
solid
Cataflam
LogP
4.218
Cataflam
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Cataflam
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Cataflam
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Cataflam
Absorption
Completely absorbed from the gastrointestinal tract.
Cataflam
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Cataflam
Patient Information
Cataflam
Organisms Affected
Humans and other mammals