Diclo-Phlogont
Brand names,
Diclo-Phlogont
Analogs
Diclo-Phlogont
Brand Names Mixture
Diclo-Phlogont
Chemical_Formula
C14H11Cl2NO2
Diclo-Phlogont
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Diclo-Phlogont
fda sheet
Diclo-Phlogont
msds (material safety sheet)
Diclo-Phlogont
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Diclo-Phlogont
Molecular Weight
296.148 g/mol
Diclo-Phlogont
Melting Point
283-285oC
Diclo-Phlogont
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Diclo-Phlogont
State
solid
Diclo-Phlogont
LogP
4.218
Diclo-Phlogont
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Diclo-Phlogont
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Diclo-Phlogont
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Diclo-Phlogont
Absorption
Completely absorbed from the gastrointestinal tract.
Diclo-Phlogont
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Diclo-Phlogont
Patient Information
Diclo-Phlogont
Organisms Affected
Humans and other mammals