Benfofen
Brand names,
Benfofen
Analogs
Benfofen
Brand Names Mixture
Benfofen
Chemical_Formula
C14H11Cl2NO2
Benfofen
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Benfofen
fda sheet
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msds (material safety sheet)
Benfofen
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Benfofen
Molecular Weight
296.148 g/mol
Benfofen
Melting Point
283-285oC
Benfofen
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Benfofen
State
solid
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LogP
4.218
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Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
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Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Benfofen
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Benfofen
Absorption
Completely absorbed from the gastrointestinal tract.
Benfofen
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Benfofen
Patient Information
Benfofen
Organisms Affected
Humans and other mammals