Voltaren SR
Brand names,
Voltaren SR
Analogs
Voltaren SR
Brand Names Mixture
Voltaren SR
Chemical_Formula
C14H11Cl2NO2
Voltaren SR
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Voltaren SR
fda sheet
Voltaren SR
msds (material safety sheet)
Voltaren SR
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Voltaren SR
Molecular Weight
296.148 g/mol
Voltaren SR
Melting Point
283-285oC
Voltaren SR
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Voltaren SR
State
solid
Voltaren SR
LogP
4.218
Voltaren SR
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Voltaren SR
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Voltaren SR
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Voltaren SR
Absorption
Completely absorbed from the gastrointestinal tract.
Voltaren SR
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Voltaren SR
Patient Information
Voltaren SR
Organisms Affected
Humans and other mammals