Dichronic
Brand names,
Dichronic
Analogs
Dichronic
Brand Names Mixture
Dichronic
Chemical_Formula
C14H11Cl2NO2
Dichronic
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Dichronic
fda sheet
Dichronic
msds (material safety sheet)
Dichronic
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Dichronic
Molecular Weight
296.148 g/mol
Dichronic
Melting Point
283-285oC
Dichronic
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Dichronic
State
solid
Dichronic
LogP
4.218
Dichronic
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Dichronic
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Dichronic
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Dichronic
Absorption
Completely absorbed from the gastrointestinal tract.
Dichronic
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Dichronic
Patient Information
Dichronic
Organisms Affected
Humans and other mammals