Voltarol
Brand names,
Voltarol
Analogs
Voltarol
Brand Names Mixture
Voltarol
Chemical_Formula
C14H11Cl2NO2
Voltarol
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Voltarol
fda sheet
Voltarol
msds (material safety sheet)
Voltarol
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Voltarol
Molecular Weight
296.148 g/mol
Voltarol
Melting Point
283-285oC
Voltarol
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Voltarol
State
solid
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LogP
4.218
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Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Voltarol
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Voltarol
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Voltarol
Absorption
Completely absorbed from the gastrointestinal tract.
Voltarol
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
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Patient Information
Voltarol
Organisms Affected
Humans and other mammals