Valetan
Brand names,
Valetan
Analogs
Valetan
Brand Names Mixture
Valetan
Chemical_Formula
C14H11Cl2NO2
Valetan
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Valetan
fda sheet
Valetan
msds (material safety sheet)
Valetan
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Valetan
Molecular Weight
296.148 g/mol
Valetan
Melting Point
283-285oC
Valetan
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Valetan
State
solid
Valetan
LogP
4.218
Valetan
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Valetan
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Valetan
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Valetan
Absorption
Completely absorbed from the gastrointestinal tract.
Valetan
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Valetan
Patient Information
Valetan
Organisms Affected
Humans and other mammals