Ecofenac
Brand names,
Ecofenac
Analogs
Ecofenac
Brand Names Mixture
Ecofenac
Chemical_Formula
C14H11Cl2NO2
Ecofenac
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Ecofenac
fda sheet
Ecofenac
msds (material safety sheet)
Ecofenac
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Ecofenac
Molecular Weight
296.148 g/mol
Ecofenac
Melting Point
283-285oC
Ecofenac
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Ecofenac
State
solid
Ecofenac
LogP
4.218
Ecofenac
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Ecofenac
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Ecofenac
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Ecofenac
Absorption
Completely absorbed from the gastrointestinal tract.
Ecofenac
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Ecofenac
Patient Information
Ecofenac
Organisms Affected
Humans and other mammals