Solaraze
Brand names,
Solaraze
Analogs
Solaraze
Brand Names Mixture
Solaraze
Chemical_Formula
C14H11Cl2NO2
Solaraze
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Solaraze
fda sheet
Solaraze
msds (material safety sheet)
Solaraze
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Solaraze
Molecular Weight
296.148 g/mol
Solaraze
Melting Point
283-285oC
Solaraze
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Solaraze
State
solid
Solaraze
LogP
4.218
Solaraze
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Solaraze
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Solaraze
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Solaraze
Absorption
Completely absorbed from the gastrointestinal tract.
Solaraze
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Solaraze
Patient Information
Solaraze
Organisms Affected
Humans and other mammals