Novapirina
Brand names,
Novapirina
Analogs
Novapirina
Brand Names Mixture
Novapirina
Chemical_Formula
C14H11Cl2NO2
Novapirina
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Novapirina
fda sheet
Novapirina
msds (material safety sheet)
Novapirina
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Novapirina
Molecular Weight
296.148 g/mol
Novapirina
Melting Point
283-285oC
Novapirina
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Novapirina
State
solid
Novapirina
LogP
4.218
Novapirina
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Novapirina
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Novapirina
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Novapirina
Absorption
Completely absorbed from the gastrointestinal tract.
Novapirina
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Novapirina
Patient Information
Novapirina
Organisms Affected
Humans and other mammals