Rhumalgan
Brand names,
Rhumalgan
Analogs
Rhumalgan
Brand Names Mixture
Rhumalgan
Chemical_Formula
C14H11Cl2NO2
Rhumalgan
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Rhumalgan
fda sheet
Rhumalgan
msds (material safety sheet)
Rhumalgan
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Rhumalgan
Molecular Weight
296.148 g/mol
Rhumalgan
Melting Point
283-285oC
Rhumalgan
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Rhumalgan
State
solid
Rhumalgan
LogP
4.218
Rhumalgan
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Rhumalgan
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Rhumalgan
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Rhumalgan
Absorption
Completely absorbed from the gastrointestinal tract.
Rhumalgan
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Rhumalgan
Patient Information
Rhumalgan
Organisms Affected
Humans and other mammals