Diclord
Brand names,
Diclord
Analogs
Diclord
Brand Names Mixture
Diclord
Chemical_Formula
C14H11Cl2NO2
Diclord
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Diclord
fda sheet
Diclord
msds (material safety sheet)
Diclord
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Diclord
Molecular Weight
296.148 g/mol
Diclord
Melting Point
283-285oC
Diclord
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Diclord
State
solid
Diclord
LogP
4.218
Diclord
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Diclord
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Diclord
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Diclord
Absorption
Completely absorbed from the gastrointestinal tract.
Diclord
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Diclord
Patient Information
Diclord
Organisms Affected
Humans and other mammals