Effekton
Brand names,
Effekton
Analogs
Effekton
Brand Names Mixture
Effekton
Chemical_Formula
C14H11Cl2NO2
Effekton
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Effekton
fda sheet
Effekton
msds (material safety sheet)
Effekton
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Effekton
Molecular Weight
296.148 g/mol
Effekton
Melting Point
283-285oC
Effekton
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Effekton
State
solid
Effekton
LogP
4.218
Effekton
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Effekton
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Effekton
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Effekton
Absorption
Completely absorbed from the gastrointestinal tract.
Effekton
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Effekton
Patient Information
Effekton
Organisms Affected
Humans and other mammals