Prophenatin
Brand names,
Prophenatin
Analogs
Prophenatin
Brand Names Mixture
Prophenatin
Chemical_Formula
C14H11Cl2NO2
Prophenatin
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Prophenatin
fda sheet
Prophenatin
msds (material safety sheet)
Prophenatin
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Prophenatin
Molecular Weight
296.148 g/mol
Prophenatin
Melting Point
283-285oC
Prophenatin
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Prophenatin
State
solid
Prophenatin
LogP
4.218
Prophenatin
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Prophenatin
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Prophenatin
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Prophenatin
Absorption
Completely absorbed from the gastrointestinal tract.
Prophenatin
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Prophenatin
Patient Information
Prophenatin
Organisms Affected
Humans and other mammals