Neriodin
Brand names,
Neriodin
Analogs
Neriodin
Brand Names Mixture
Neriodin
Chemical_Formula
C14H11Cl2NO2
Neriodin
RX_link
http://www.rxlist.com/cgi/generic/diclofen.htm
Neriodin
fda sheet
Neriodin
msds (material safety sheet)
Neriodin
Synthesis Reference
A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)
Neriodin
Molecular Weight
296.148 g/mol
Neriodin
Melting Point
283-285oC
Neriodin
H2O Solubility
0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)
Neriodin
State
solid
Neriodin
LogP
4.218
Neriodin
Dosage Forms
Tablet (extended-release); Tablet (immediate-release)
Neriodin
Indication
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Neriodin
Pharmacology
Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis
Neriodin
Absorption
Completely absorbed from the gastrointestinal tract.
Neriodin
side effects and Toxicity
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)
Neriodin
Patient Information
Neriodin
Organisms Affected
Humans and other mammals