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Diclofenac Brand names, Diclofenac Analogs

Diclofenac Brand Names Mixture

  • No information avaliable

Diclofenac Chemical_Formula

C14H11Cl2NO2

Diclofenac RX_link

http://www.rxlist.com/cgi/generic/diclofen.htm

Diclofenac fda sheet

Diclofenac FDA

Diclofenac msds (material safety sheet)

Diclofenac MSDS

Diclofenac Synthesis Reference

A. Sallman, R. Pfister, U.S. Pat. 3,558,690, (1971)

Diclofenac Molecular Weight

296.148 g/mol

Diclofenac Melting Point

283-285oC

Diclofenac H2O Solubility

0.00082 mg/mL (Na salt); 2.43 mg/mL (K salt)

Diclofenac State

solid

Diclofenac LogP

4.218

Diclofenac Dosage Forms

Tablet (extended-release); Tablet (immediate-release)

Diclofenac Indication

For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.

Diclofenac Pharmacology

Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis

Diclofenac Absorption

Completely absorbed from the gastrointestinal tract.

Diclofenac side effects and Toxicity

Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD50=390mg/kg (orally in mice)

Diclofenac Patient Information

Diclofenac Organisms Affected

Humans and other mammals