Spruehpflanzol
Category
Spruehpflanzol Brand names, Spruehpflanzol Analogs
Spruehpflanzol Brand Names Mixture
Spruehpflanzol Chemical_Formula
C24H31ClO7
Spruehpflanzol RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Spruehpflanzol fda sheet
Spruehpflanzol msds (material safety sheet)
Spruehpflanzol Synthesis Reference
No information avaliable
Spruehpflanzol Molecular Weight
466.951 g/mol
Spruehpflanzol Melting Point
220-224 oC
Spruehpflanzol H2O Solubility
5 mg/mL
Spruehpflanzol State
Solid
Spruehpflanzol LogP
4.004
Spruehpflanzol Dosage Forms
Solution; Spray
Spruehpflanzol Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Spruehpflanzol Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Spruehpflanzol Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Spruehpflanzol side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Spruehpflanzol Patient Information
Spruehpflanzol Organisms Affected
Humans and other mammals
