Omnitox
Category
Omnitox Brand names, Omnitox Analogs
Omnitox Brand Names Mixture
Omnitox Chemical_Formula
C24H31ClO7
Omnitox RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Omnitox fda sheet
Omnitox msds (material safety sheet)
Omnitox Synthesis Reference
No information avaliable
Omnitox Molecular Weight
466.951 g/mol
Omnitox Melting Point
220-224 oC
Omnitox H2O Solubility
5 mg/mL
Omnitox State
Solid
Omnitox LogP
4.004
Omnitox Dosage Forms
Solution; Spray
Omnitox Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Omnitox Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Omnitox Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Omnitox side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Omnitox Patient Information
Omnitox Organisms Affected
Humans and other mammals
