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Hexyclan Brand names, Hexyclan Analogs

Hexyclan Brand Names Mixture

  • No information avaliable

Hexyclan Chemical_Formula

C24H31ClO7

Hexyclan RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Hexyclan fda sheet

Hexyclan FDA

Hexyclan msds (material safety sheet)

Hexyclan MSDS

Hexyclan Synthesis Reference

No information avaliable

Hexyclan Molecular Weight

466.951 g/mol

Hexyclan Melting Point

220-224 oC

Hexyclan H2O Solubility

5 mg/mL

Hexyclan State

Solid

Hexyclan LogP

4.004

Hexyclan Dosage Forms

Solution; Spray

Hexyclan Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Hexyclan Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Hexyclan Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Hexyclan side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Hexyclan Patient Information

Hexyclan Organisms Affected

Humans and other mammals