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BBH Brand names, BBH Analogs

BBH Brand Names Mixture

  • No information avaliable

BBH Chemical_Formula

C24H31ClO7

BBH RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

BBH fda sheet

BBH FDA

BBH msds (material safety sheet)

BBH MSDS

BBH Synthesis Reference

No information avaliable

BBH Molecular Weight

466.951 g/mol

BBH Melting Point

220-224 oC

BBH H2O Solubility

5 mg/mL

BBH State

Solid

BBH LogP

4.004

BBH Dosage Forms

Solution; Spray

BBH Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

BBH Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

BBH Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

BBH side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

BBH Patient Information

BBH Organisms Affected

Humans and other mammals