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Nexit-Stark Brand names, Nexit-Stark Analogs

Nexit-Stark Brand Names Mixture

  • No information avaliable

Nexit-Stark Chemical_Formula

C24H31ClO7

Nexit-Stark RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Nexit-Stark fda sheet

Nexit-Stark FDA

Nexit-Stark msds (material safety sheet)

Nexit-Stark MSDS

Nexit-Stark Synthesis Reference

No information avaliable

Nexit-Stark Molecular Weight

466.951 g/mol

Nexit-Stark Melting Point

220-224 oC

Nexit-Stark H2O Solubility

5 mg/mL

Nexit-Stark State

Solid

Nexit-Stark LogP

4.004

Nexit-Stark Dosage Forms

Solution; Spray

Nexit-Stark Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Nexit-Stark Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Nexit-Stark Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Nexit-Stark side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Nexit-Stark Patient Information

Nexit-Stark Organisms Affected

Humans and other mammals