Benzene hexachloride
Category
Benzene hexachloride Brand names, Benzene hexachloride Analogs
Benzene hexachloride Brand Names Mixture
Benzene hexachloride Chemical_Formula
C24H31ClO7
Benzene hexachloride RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Benzene hexachloride fda sheet
Benzene hexachloride msds (material safety sheet)
Benzene hexachloride Synthesis Reference
No information avaliable
Benzene hexachloride Molecular Weight
466.951 g/mol
Benzene hexachloride Melting Point
220-224 oC
Benzene hexachloride H2O Solubility
5 mg/mL
Benzene hexachloride State
Solid
Benzene hexachloride LogP
4.004
Benzene hexachloride Dosage Forms
Solution; Spray
Benzene hexachloride Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Benzene hexachloride Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Benzene hexachloride Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Benzene hexachloride side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Benzene hexachloride Patient Information
Benzene hexachloride Organisms Affected
Humans and other mammals
