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Gamene Brand names, Gamene Analogs

Gamene Brand Names Mixture

  • No information avaliable

Gamene Chemical_Formula

C24H31ClO7

Gamene RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Gamene fda sheet

Gamene FDA

Gamene msds (material safety sheet)

Gamene MSDS

Gamene Synthesis Reference

No information avaliable

Gamene Molecular Weight

466.951 g/mol

Gamene Melting Point

220-224 oC

Gamene H2O Solubility

5 mg/mL

Gamene State

Solid

Gamene LogP

4.004

Gamene Dosage Forms

Solution; Spray

Gamene Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Gamene Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Gamene Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Gamene side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Gamene Patient Information

Gamene Organisms Affected

Humans and other mammals