Streunex
Category
Streunex Brand names, Streunex Analogs
Streunex Brand Names Mixture
Streunex Chemical_Formula
C24H31ClO7
Streunex RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Streunex fda sheet
Streunex msds (material safety sheet)
Streunex Synthesis Reference
No information avaliable
Streunex Molecular Weight
466.951 g/mol
Streunex Melting Point
220-224 oC
Streunex H2O Solubility
5 mg/mL
Streunex State
Solid
Streunex LogP
4.004
Streunex Dosage Forms
Solution; Spray
Streunex Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Streunex Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Streunex Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Streunex side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Streunex Patient Information
Streunex Organisms Affected
Humans and other mammals
