Nexen FB en es it fr

Nexen FB Brand names, Nexen FB Analogs

Nexen FB Brand Names Mixture

  • No information avaliable

Nexen FB Chemical_Formula

C24H31ClO7

Nexen FB RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Nexen FB fda sheet

Nexen_FB FDA

Nexen FB msds (material safety sheet)

Nexen_FB MSDS

Nexen FB Synthesis Reference

No information avaliable

Nexen FB Molecular Weight

466.951 g/mol

Nexen FB Melting Point

220-224 oC

Nexen FB H2O Solubility

5 mg/mL

Nexen FB State

Solid

Nexen FB LogP

4.004

Nexen FB Dosage Forms

Solution; Spray

Nexen FB Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Nexen FB Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Nexen FB Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Nexen FB side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Nexen FB Patient Information

Nexen FB Organisms Affected

Humans and other mammals