Gamma-Col Brand names, Gamma-Col Analogs
Gamma-Col Brand Names Mixture
Gamma-Col fda sheet
Gamma-Col msds (material safety sheet)
Gamma-Col Synthesis Reference
No information avaliable
Gamma-Col Molecular Weight
Gamma-Col Melting Point
Gamma-Col H2O Solubility
Gamma-Col Dosage Forms
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Very limited systemic absorption, but good absorption at the point of delivery.
Gamma-Col side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Gamma-Col Patient Information
Gamma-Col Organisms Affected
Humans and other mammals