Drilltox-Spezial Aglukon
Category
Drilltox-Spezial Aglukon Brand names, Drilltox-Spezial Aglukon Analogs
Drilltox-Spezial Aglukon Brand Names Mixture
Drilltox-Spezial Aglukon Chemical_Formula
C24H31ClO7
Drilltox-Spezial Aglukon RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Drilltox-Spezial Aglukon fda sheet
Drilltox-Spezial Aglukon msds (material safety sheet)
Drilltox-Spezial Aglukon Synthesis Reference
No information avaliable
Drilltox-Spezial Aglukon Molecular Weight
466.951 g/mol
Drilltox-Spezial Aglukon Melting Point
220-224 oC
Drilltox-Spezial Aglukon H2O Solubility
5 mg/mL
Drilltox-Spezial Aglukon State
Solid
Drilltox-Spezial Aglukon LogP
4.004
Drilltox-Spezial Aglukon Dosage Forms
Solution; Spray
Drilltox-Spezial Aglukon Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Drilltox-Spezial Aglukon Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Drilltox-Spezial Aglukon Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Drilltox-Spezial Aglukon side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Drilltox-Spezial Aglukon Patient Information
Drilltox-Spezial Aglukon Organisms Affected
Humans and other mammals