Lindafor
Category
Lindafor Brand names, Lindafor Analogs
Lindafor Brand Names Mixture
Lindafor Chemical_Formula
C24H31ClO7
Lindafor RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Lindafor fda sheet
Lindafor msds (material safety sheet)
Lindafor Synthesis Reference
No information avaliable
Lindafor Molecular Weight
466.951 g/mol
Lindafor Melting Point
220-224 oC
Lindafor H2O Solubility
5 mg/mL
Lindafor State
Solid
Lindafor LogP
4.004
Lindafor Dosage Forms
Solution; Spray
Lindafor Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Lindafor Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Lindafor Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Lindafor side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Lindafor Patient Information
Lindafor Organisms Affected
Humans and other mammals
