Aalindan
Category
Aalindan Brand names, Aalindan Analogs
Aalindan Brand Names Mixture
Aalindan Chemical_Formula
C24H31ClO7
Aalindan RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Aalindan fda sheet
Aalindan msds (material safety sheet)
Aalindan Synthesis Reference
No information avaliable
Aalindan Molecular Weight
466.951 g/mol
Aalindan Melting Point
220-224 oC
Aalindan H2O Solubility
5 mg/mL
Aalindan State
Solid
Aalindan LogP
4.004
Aalindan Dosage Forms
Solution; Spray
Aalindan Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Aalindan Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Aalindan Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Aalindan side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Aalindan Patient Information
Aalindan Organisms Affected
Humans and other mammals
