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Dol Granule Brand names, Dol Granule Analogs

Dol Granule Brand Names Mixture

  • No information avaliable

Dol Granule Chemical_Formula

C24H31ClO7

Dol Granule RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Dol Granule fda sheet

Dol_Granule FDA

Dol Granule msds (material safety sheet)

Dol_Granule MSDS

Dol Granule Synthesis Reference

No information avaliable

Dol Granule Molecular Weight

466.951 g/mol

Dol Granule Melting Point

220-224 oC

Dol Granule H2O Solubility

5 mg/mL

Dol Granule State

Solid

Dol Granule LogP

4.004

Dol Granule Dosage Forms

Solution; Spray

Dol Granule Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Dol Granule Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Dol Granule Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Dol Granule side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Dol Granule Patient Information

Dol Granule Organisms Affected

Humans and other mammals