Gammalin 20
Category
Gammalin 20 Brand names, Gammalin 20 Analogs
Gammalin 20 Brand Names Mixture
Gammalin 20 Chemical_Formula
C24H31ClO7
Gammalin 20 RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Gammalin 20 fda sheet
Gammalin 20 msds (material safety sheet)
Gammalin 20 Synthesis Reference
No information avaliable
Gammalin 20 Molecular Weight
466.951 g/mol
Gammalin 20 Melting Point
220-224 oC
Gammalin 20 H2O Solubility
5 mg/mL
Gammalin 20 State
Solid
Gammalin 20 LogP
4.004
Gammalin 20 Dosage Forms
Solution; Spray
Gammalin 20 Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Gammalin 20 Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Gammalin 20 Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Gammalin 20 side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Gammalin 20 Patient Information
Gammalin 20 Organisms Affected
Humans and other mammals
