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Lindex Brand names, Lindex Analogs

Lindex Brand Names Mixture

  • No information avaliable

Lindex Chemical_Formula

C24H31ClO7

Lindex RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Lindex fda sheet

Lindex FDA

Lindex msds (material safety sheet)

Lindex MSDS

Lindex Synthesis Reference

No information avaliable

Lindex Molecular Weight

466.951 g/mol

Lindex Melting Point

220-224 oC

Lindex H2O Solubility

5 mg/mL

Lindex State

Solid

Lindex LogP

4.004

Lindex Dosage Forms

Solution; Spray

Lindex Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Lindex Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Lindex Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Lindex side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Lindex Patient Information

Lindex Organisms Affected

Humans and other mammals