Agrocide III
Category
Agrocide III Brand names, Agrocide III Analogs
Agrocide III Brand Names Mixture
Agrocide III Chemical_Formula
C24H31ClO7
Agrocide III RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Agrocide III fda sheet
Agrocide III msds (material safety sheet)
Agrocide III Synthesis Reference
No information avaliable
Agrocide III Molecular Weight
466.951 g/mol
Agrocide III Melting Point
220-224 oC
Agrocide III H2O Solubility
5 mg/mL
Agrocide III State
Solid
Agrocide III LogP
4.004
Agrocide III Dosage Forms
Solution; Spray
Agrocide III Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Agrocide III Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Agrocide III Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Agrocide III side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Agrocide III Patient Information
Agrocide III Organisms Affected
Humans and other mammals
