Lindosep
Category
Lindosep Brand names, Lindosep Analogs
Lindosep Brand Names Mixture
Lindosep Chemical_Formula
C24H31ClO7
Lindosep RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Lindosep fda sheet
Lindosep msds (material safety sheet)
Lindosep Synthesis Reference
No information avaliable
Lindosep Molecular Weight
466.951 g/mol
Lindosep Melting Point
220-224 oC
Lindosep H2O Solubility
5 mg/mL
Lindosep State
Solid
Lindosep LogP
4.004
Lindosep Dosage Forms
Solution; Spray
Lindosep Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Lindosep Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Lindosep Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Lindosep side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Lindosep Patient Information
Lindosep Organisms Affected
Humans and other mammals
