Agrocide
Category
Agrocide Brand names, Agrocide Analogs
Agrocide Brand Names Mixture
Agrocide Chemical_Formula
C24H31ClO7
Agrocide RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Agrocide fda sheet
Agrocide msds (material safety sheet)
Agrocide Synthesis Reference
No information avaliable
Agrocide Molecular Weight
466.951 g/mol
Agrocide Melting Point
220-224 oC
Agrocide H2O Solubility
5 mg/mL
Agrocide State
Solid
Agrocide LogP
4.004
Agrocide Dosage Forms
Solution; Spray
Agrocide Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Agrocide Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Agrocide Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Agrocide side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Agrocide Patient Information
Agrocide Organisms Affected
Humans and other mammals
