PharmacyCodes



Ben-Hex en es it fr

Ben-Hex Brand names, Ben-Hex Analogs

Ben-Hex Brand Names Mixture

  • No information avaliable

Ben-Hex Chemical_Formula

C24H31ClO7

Ben-Hex RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Ben-Hex fda sheet

Ben-Hex FDA

Ben-Hex msds (material safety sheet)

Ben-Hex MSDS

Ben-Hex Synthesis Reference

No information avaliable

Ben-Hex Molecular Weight

466.951 g/mol

Ben-Hex Melting Point

220-224 oC

Ben-Hex H2O Solubility

5 mg/mL

Ben-Hex State

Solid

Ben-Hex LogP

4.004

Ben-Hex Dosage Forms

Solution; Spray

Ben-Hex Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Ben-Hex Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Ben-Hex Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Ben-Hex side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Ben-Hex Patient Information

Ben-Hex Organisms Affected

Humans and other mammals