PharmacyCodes



Milbol 49 en es it fr

Milbol 49 Brand names, Milbol 49 Analogs

Milbol 49 Brand Names Mixture

  • No information avaliable

Milbol 49 Chemical_Formula

C24H31ClO7

Milbol 49 RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Milbol 49 fda sheet

Milbol_49 FDA

Milbol 49 msds (material safety sheet)

Milbol_49 MSDS

Milbol 49 Synthesis Reference

No information avaliable

Milbol 49 Molecular Weight

466.951 g/mol

Milbol 49 Melting Point

220-224 oC

Milbol 49 H2O Solubility

5 mg/mL

Milbol 49 State

Solid

Milbol 49 LogP

4.004

Milbol 49 Dosage Forms

Solution; Spray

Milbol 49 Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Milbol 49 Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Milbol 49 Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Milbol 49 side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Milbol 49 Patient Information

Milbol 49 Organisms Affected

Humans and other mammals