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Thacapzol Brand names, Thacapzol Analogs

Thacapzol Brand Names Mixture

  • No information avaliable

Thacapzol Chemical_Formula


Thacapzol RX_link

Thacapzol fda sheet

Thacapzol msds (material safety sheet)

Thacapzol MSDS

Thacapzol Synthesis Reference

No information avaliable

Thacapzol Molecular Weight

114.17 g/mol

Thacapzol Melting Point

146 oC

Thacapzol H2O Solubility

275 g/L

Thacapzol State


Thacapzol LogP


Thacapzol Dosage Forms

Tablet (5 or 10 mg)

Thacapzol Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Thacapzol Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Thacapzol Absorption

Rapid with an oral bioavailability of 93%.

Thacapzol side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Thacapzol Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Thacapzol Organisms Affected

Humans and other mammals