Danantizol

Danantizol Brand names, Danantizol Analogs

Danantizol Brand Names Mixture

No information avaliable

Danantizol Chemical_Formula

C₄H₆N₂S

Danantizol RX_link

http://www.rxlist.com/cgi/generic3/methim.htm

Danantizol fda sheet

Danantizol msds (material safety sheet)

Danantizol MSDS

Danantizol Synthesis Reference

No information avaliable

Danantizol Molecular Weight

114.17 g/mol

Danantizol Melting Point

146 ^oC

Danantizol H₂O Solubility

275 g/L

Danantizol State

Solid

Danantizol LogP

-0.34

Danantizol Dosage Forms

Tablet (5 or 10 mg)

Danantizol Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Danantizol Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Danantizol Absorption

Rapid with an oral bioavailability of 93%.

Danantizol side effects and Toxicity

Oral LD₅₀ in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Danantizol Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Danantizol Organisms Affected

Humans and other mammals