Methimazol en es it fr

Methimazol Brand names, Methimazol Analogs

Methimazol Brand Names Mixture

  • No information avaliable

Methimazol Chemical_Formula


Methimazol RX_link

Methimazol fda sheet

Methimazol msds (material safety sheet)

Methimazol MSDS

Methimazol Synthesis Reference

No information avaliable

Methimazol Molecular Weight

114.17 g/mol

Methimazol Melting Point

146 oC

Methimazol H2O Solubility

275 g/L

Methimazol State


Methimazol LogP


Methimazol Dosage Forms

Tablet (5 or 10 mg)

Methimazol Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Methimazol Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Methimazol Absorption

Rapid with an oral bioavailability of 93%.

Methimazol side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Methimazol Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Methimazol Organisms Affected

Humans and other mammals