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Merkastan Brand names, Merkastan Analogs

Merkastan Brand Names Mixture

  • No information avaliable

Merkastan Chemical_Formula


Merkastan RX_link

Merkastan fda sheet

Merkastan msds (material safety sheet)

Merkastan MSDS

Merkastan Synthesis Reference

No information avaliable

Merkastan Molecular Weight

114.17 g/mol

Merkastan Melting Point

146 oC

Merkastan H2O Solubility

275 g/L

Merkastan State


Merkastan LogP


Merkastan Dosage Forms

Tablet (5 or 10 mg)

Merkastan Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Merkastan Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Merkastan Absorption

Rapid with an oral bioavailability of 93%.

Merkastan side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Merkastan Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Merkastan Organisms Affected

Humans and other mammals