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Thimazole Brand names, Thimazole Analogs

Thimazole Brand Names Mixture

  • No information avaliable

Thimazole Chemical_Formula


Thimazole RX_link

Thimazole fda sheet

Thimazole msds (material safety sheet)

Thimazole MSDS

Thimazole Synthesis Reference

No information avaliable

Thimazole Molecular Weight

114.17 g/mol

Thimazole Melting Point

146 oC

Thimazole H2O Solubility

275 g/L

Thimazole State


Thimazole LogP


Thimazole Dosage Forms

Tablet (5 or 10 mg)

Thimazole Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Thimazole Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Thimazole Absorption

Rapid with an oral bioavailability of 93%.

Thimazole side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Thimazole Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Thimazole Organisms Affected

Humans and other mammals