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Frentirox Brand names, Frentirox Analogs

Frentirox Brand Names Mixture

  • No information avaliable

Frentirox Chemical_Formula


Frentirox RX_link

Frentirox fda sheet

Frentirox msds (material safety sheet)

Frentirox MSDS

Frentirox Synthesis Reference

No information avaliable

Frentirox Molecular Weight

114.17 g/mol

Frentirox Melting Point

146 oC

Frentirox H2O Solubility

275 g/L

Frentirox State


Frentirox LogP


Frentirox Dosage Forms

Tablet (5 or 10 mg)

Frentirox Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Frentirox Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Frentirox Absorption

Rapid with an oral bioavailability of 93%.

Frentirox side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Frentirox Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Frentirox Organisms Affected

Humans and other mammals