USAF EL-30

USAF EL-30 Brand names, USAF EL-30 Analogs

USAF EL-30 Brand Names Mixture

No information avaliable

USAF EL-30 Chemical_Formula

C₄H₆N₂S

USAF EL-30 RX_link

http://www.rxlist.com/cgi/generic3/methim.htm

USAF EL-30 fda sheet

USAF EL-30 msds (material safety sheet)

USAF_EL-30 MSDS

USAF EL-30 Synthesis Reference

No information avaliable

USAF EL-30 Molecular Weight

114.17 g/mol

USAF EL-30 Melting Point

146 ^oC

USAF EL-30 H₂O Solubility

275 g/L

USAF EL-30 State

Solid

USAF EL-30 LogP

-0.34

USAF EL-30 Dosage Forms

Tablet (5 or 10 mg)

USAF EL-30 Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

USAF EL-30 Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

USAF EL-30 Absorption

Rapid with an oral bioavailability of 93%.

USAF EL-30 side effects and Toxicity

Oral LD₅₀ in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

USAF EL-30 Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

USAF EL-30 Organisms Affected

Humans and other mammals