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Metazolo Brand names, Metazolo Analogs

Metazolo Brand Names Mixture

  • No information avaliable

Metazolo Chemical_Formula


Metazolo RX_link

Metazolo fda sheet

Metazolo msds (material safety sheet)

Metazolo MSDS

Metazolo Synthesis Reference

No information avaliable

Metazolo Molecular Weight

114.17 g/mol

Metazolo Melting Point

146 oC

Metazolo H2O Solubility

275 g/L

Metazolo State


Metazolo LogP


Metazolo Dosage Forms

Tablet (5 or 10 mg)

Metazolo Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Metazolo Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Metazolo Absorption

Rapid with an oral bioavailability of 93%.

Metazolo side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Metazolo Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Metazolo Organisms Affected

Humans and other mammals