Propyl-Thyracil en es it fr

Propyl-Thyracil Brand names, Propyl-Thyracil Analogs

Propyl-Thyracil Brand Names Mixture

  • No information avaliable

Propyl-Thyracil Chemical_Formula


Propyl-Thyracil RX_link

Propyl-Thyracil fda sheet

Propyl-Thyracil msds (material safety sheet)

Propyl-Thyracil MSDS

Propyl-Thyracil Synthesis Reference

No information avaliable

Propyl-Thyracil Molecular Weight

114.17 g/mol

Propyl-Thyracil Melting Point

146 oC

Propyl-Thyracil H2O Solubility

275 g/L

Propyl-Thyracil State


Propyl-Thyracil LogP


Propyl-Thyracil Dosage Forms

Tablet (5 or 10 mg)

Propyl-Thyracil Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Propyl-Thyracil Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Propyl-Thyracil Absorption

Rapid with an oral bioavailability of 93%.

Propyl-Thyracil side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Propyl-Thyracil Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Propyl-Thyracil Organisms Affected

Humans and other mammals