Thymidazol

Thymidazol Brand names, Thymidazol Analogs

Thymidazol Brand Names Mixture

No information avaliable

Thymidazol Chemical_Formula

C₄H₆N₂S

Thymidazol RX_link

http://www.rxlist.com/cgi/generic3/methim.htm

Thymidazol fda sheet

Thymidazol msds (material safety sheet)

Thymidazol MSDS

Thymidazol Synthesis Reference

No information avaliable

Thymidazol Molecular Weight

114.17 g/mol

Thymidazol Melting Point

146 ^oC

Thymidazol H₂O Solubility

275 g/L

Thymidazol State

Solid

Thymidazol LogP

-0.34

Thymidazol Dosage Forms

Tablet (5 or 10 mg)

Thymidazol Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Thymidazol Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Thymidazol Absorption

Rapid with an oral bioavailability of 93%.

Thymidazol side effects and Toxicity

Oral LD₅₀ in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Thymidazol Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Thymidazol Organisms Affected

Humans and other mammals