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Metothyrin Brand names, Metothyrin Analogs

Metothyrin Brand Names Mixture

  • No information avaliable

Metothyrin Chemical_Formula


Metothyrin RX_link

Metothyrin fda sheet

Metothyrin msds (material safety sheet)

Metothyrin MSDS

Metothyrin Synthesis Reference

No information avaliable

Metothyrin Molecular Weight

114.17 g/mol

Metothyrin Melting Point

146 oC

Metothyrin H2O Solubility

275 g/L

Metothyrin State


Metothyrin LogP


Metothyrin Dosage Forms

Tablet (5 or 10 mg)

Metothyrin Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Metothyrin Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Metothyrin Absorption

Rapid with an oral bioavailability of 93%.

Metothyrin side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Metothyrin Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Metothyrin Organisms Affected

Humans and other mammals