Thycapsol
Thycapsol Brand names, Thycapsol Analogs
- Basolan
- Danantizol
- Favistan
- Frentirox
- Mercaptazole
- Mercasolyl
- Mercazole
- Mercazolyl
- Merkastan
- Merkazolil
- Metazolo
- Methamazole
- Methiamazole
- Methimazol
- Methylmercaptoimidazole
- Metizol
- Metothyrin
- Metothyrine
- Metotirin
- Propyl-Thyracil
- Strumazol
- Strumazole
- Tapazole
- Tapuzole
- Thacapzol
- Thiamazol
- Thiamazole
- Thimazole
- Thycapsol
- Thycapzol
- Thymidazol
- Thymidazole
- USAF EL-30
Thycapsol Brand Names Mixture
- No information avaliable
Thycapsol Chemical_Formula
C4H6N2S
Thycapsol RX_link
http://www.rxlist.com/cgi/generic3/methim.htm
Thycapsol fda sheet
Thycapsol msds (material safety sheet)
Thycapsol Synthesis Reference
No information avaliable
Thycapsol Molecular Weight
114.17 g/mol
Thycapsol Melting Point
146 oC
Thycapsol H2O Solubility
275 g/L
Thycapsol State
Solid
Thycapsol LogP
-0.34
Thycapsol Dosage Forms
Tablet (5 or 10 mg)
Thycapsol Indication
For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.
Thycapsol Pharmacology
Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.
Thycapsol Absorption
Rapid with an oral bioavailability of 93%.
Thycapsol side effects and Toxicity
Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.
Thycapsol Patient Information
Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.
Thycapsol Organisms Affected
Humans and other mammals
